Alpha-Ketoglutarate

18/Description

About

Alpha-ketoglutarate is a chemical found in the body. People use it to make medicine.

Alpha-ketoglutarate is used for kidney disease; intestinal and stomach disorders, including bacterial infections; liver problems; cataracts; and recurring yeast infections. It is also used for improving the way kidney patients receiving hemodialysis treatments process protein.

Some people take alpha-ketoglutarate to improve peak athletic performance. Suppliers of athletic nutritional supplements claim alpha-ketoglutaric acid may be an important addition to proper diet and training for the athlete who wants peak performance. They base this claim on studies that show extra ammonia in the body can combine with alpha-ketoglutarate to reduce problems associated with too much ammonia (ammonia toxicity). But, so far, the only studies that show alpha-ketoglutarate can reduce ammonia toxicity have been performed in hemodialysis patients.

Healthcare providers sometimes give alpha-ketoglutarate intravenously (by IV) for preventing injury to the heart caused by blood flow problems during heart surgery and for preventing muscle breakdown after surgery or trauma.

How it works

Alpha-ketoglutarate works in many pathways in the body, to help make muscle, and to help heal wounds.

Effectiveness

Possibly Effective
Improving kidney failure treatment (hemodialysis)

Taking calcium alpha-ketoglutarate seems to improve results of certain lab tests used to monitor the effectiveness of hemodialysis in patients receiving this treatment.

Preventing blood supply problems during heart surgery

Administering alpha-ketoglutarate intravenously (by IV) seems to reduce blood supply problems during heart surgery.

Preventing muscle breakdown

Alpha-ketoglutarate seems to reduce muscle breakdown after surgery or trauma.

Concerns

Possibly safe

Alpha-ketoglutarate is POSSIBLY SAFE for most adults when used appropriately.

18/Warnings

Warnings

Pregnancy and breast-feeding: Not enough is known about the use of alpha-ketoglutarate duringpregnancyandbreast-feeding. Stay on the safe side and avoid use.Dosing considerations for Alpha-ketoglutarate.

Interactions

No information available.

The information provided on this page is for reference purposes and is not meant to be used as a medical advice, diagnosis or treatment. Always consult with a medical professional. The content on this page has been provided with thanks by RxList.com