Borage

Botanicals

18/Description

About

Borage is a plant. Its flowers and leaves, as well as the oil from its seeds are used as medicine.

Borage seed oil is used for skin disorders including eczema, seborrheic dermatitis, and neurodermatitis. It is also used for rheumatoid arthritis (RA), stress, premenstrual syndrome (PMS), diabetes, attention deficit-hyperactivity disorder (ADHD), acute respiratory distress syndrome (ARDS), alcoholism, pain and swelling (inflammation), and for preventing heart disease and stroke.

Borage flower and leaves are used for fever, cough, and depression.

Borage is also used for a hormone problem called adrenal insufficiency, for "blood purification," to increase urine flow, to prevent inflammation of the lungs, as a sedative, and to promote sweating. Borage is also used to increase breast milk production and to treat bronchitis and colds.

Borage is applied to the skin for infantile seborrheic dermatitis and is also used in a dressing to soften the skin.

In foods, borage is eaten in salads and soups.

In manufacturing, borage is used in skin care products.

How it works

Borage seed oil contains a fatty acid called gamma-linolenic acid (GLA). GLA seems to have anti-inflammatory effects. Borage flower might have an antioxidant effect.

Effectiveness

Possibly Effective
Improving the function of the lungs in critically ill patients

There is some evidence that borage seed oil, when taken by mouth in combination with eicosapentaenoic acid (EPA), might reduce the number of days spent in the intensive care unit (ICU) and the length of time a breathing machine is needed by patients with acute respiratory distress syndrome (ARDS).

Growth and development in premature infants

Infant formula supplemented with fatty acids from borage oil and fish oils seems to improve growth and development of the nervous system in infants born early, especially boys.

Rheumatoid arthritis (RA)

There is some evidence that taking borage seed oil in combination with conventional painkilling or anti-inflammatory medications might help decrease symptoms of RA after six weeks of treatment. The improvement appears to last for up to 24 weeks. Improvement is measured as a decrease in the number and severity of tender and swollen joints.

Concerns

Possibly safe

Borage seed oil is POSSIBLY SAFE when taken by mouth or applied to the skin appropriately

Likely unsafe

Borage seed oil is LIKELY UNSAFE when products containing a dangerous chemicals called pyrrolizidine alkaloids (PAs) are taken by mouth. Borage plant parts including the leaf, flower, and seed can contain PAs. PAs can damage the liver or cause cancer, especially when used in high doses or for a long time. Only use products that are certified and labeled PA-free.

18/Warnings

Warnings

Children: Borage see oil isPOSSIBLY SAFEwhen taken by mouth appropriately. Borage seed oil isLIKELY UNSAFEwhen products containing PA are taken by mouth.

Pregnancy and breast-feeding: Borage seed oil is LIKELY UNSAFE during pregnancy and while breast-feeding. It is important to avoid borage products that might contain pyrrolizidine alkaloids (PAs). PAs are a risk to the mother because they can cause serious liver disease and might cause cancer. PAs are also a risk to the infant because they might cause birth defects and they can pass into breast milk. Researchers are not sure if borage products that are certified PA-free are safe during pregnancy and breast-feeding. It is best to stay safe and avoid using borage.

Bleeding disorders: There is some concern that borage seed oil might prolong bleeding time and increase the risk of bruising and bleeding. If you have a bleeding disorder, use borage with caution.

Liver disease: Borage products containing hepatotoxic pyrrolizidine alkaloids (PA) might make liver disease worse.

Surgery: Borage might increase the risk of bleeding during and after surgery. Stop taking borage at least 2 weeks before a scheduled surgery.

Interactions

Always consult with your doctor.
Moderate
Medications used during surgery (Anesthesia)

Borage is broken down by the liver. Some chemicals that form when the liver breaks down borage seed oil can be harmful. Medications that cause the liver to break down borage seed oil might enhance the toxic effects of chemicals contained in borage seed oil.Some of these medicines include carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), and others.Borage seed oil might slow blood clotting in some people. Borage seed oil contains GLA (gamma linolenic acid). GLA is the part of borage seed oil that might slow blood clotting.Taking borage seed oil along with medications that also slow clotting might increase the chances of bruising and bleeding.Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.Borage seed oil might interact with medications used during surgery. Be sure to tell your doctor what natural products you are taking before having surgery. To be on the safe side, you should stop taking borage seed oil at least two weeks before surgery.

Minor
NSAIDs (Nonsteroidal anti-inflammatory drugs)

NSAIDs are anti-inflammatory medications used to decrease pain and swelling. Borage seed oil is also used as an anti-inflammatory medication. Sometimes NSAIDs and borage seed oil are used together for rheumatoid arthritis. However, borage seed oil seems to work in a different way than NSAIDs. Some scientists think that taking NSAIDs along with borage seed oil might decrease the effectiveness of borage seed oil. But it is too soon to know if this is true.Some NSAIDs include ibuprofen (Advil, Motrin, Nuprin, others), indomethacin (Indocin), naproxen (Aleve, Anaprox, Naprelan, Naprosyn), piroxicam (Feldene), aspirin, and others.

The information provided on this page is for reference purposes and is not meant to be used as a medical advice, diagnosis or treatment. Always consult with a medical professional. The content on this page has been provided with thanks by RxList.com