Goldthread is a plant. The underground stem (rhizome) is used to make medicine.

Goldthread is used for digestive disorders, parasite infections including leishmaniasis, and trichomoniasis, and a skin condition called psoriasis.

How it works

Goldthread might decrease acid in the stomach. It also appears to have antibacterial effects.


Not Proven
Digestive problems
Leishmaniasis (a parasite infection that affects the skin)
Trichomoniasis (a parasite infection that is transmitted sexually)
Psoriasis (a skin condition)
Other conditions



Goldthread is UNSAFE in newborn infants.

There is not enough information to know if goldthread is safe in medicinal amounts



Children: Goldthread isUNSAFEin children. It contains a chemical called berberine that can increase the amount ofbilirubinin newborns. Bilirubin is a chemical released by theliver. Too much bilirubin can lead to permanentbraindamage in newborns, especially in newborns born too early.Are there any interactions with medications?

Pregnancy and breast-feeding: Goldthread is UNSAFE during pregnancy. It contains a chemical called berberine that is thought to cross the placenta and may cause harm to the developing child. Brain damage due to too much bilirubin has developed in newborn infants exposed to berberine. Beginning research suggests pregnant women who take goldthread during the first three months of pregnancy increase the risk that their newborns will have birth defects affecting the central nervous system.

It's also UNSAFE for breast-feeding mothers to take goldthread. Berberine and other harmful chemicals in goldthread can be transferred to the infant through breast milk.


Always consult with your doctor.
Cyclosporine (Neoral, Sandimmune)

The body breaks down cyclosporine (Neoral, Sandimmune) to get rid of it. Goldthread might decrease how fast the body breaks down cyclosporine (Neoral, Sandimmune). This might cause there to be too much cyclosporine (Neoral, Sandimmune) in the body and potentially cause side effects.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)

Some medications are changed and broken down by the liver. Goldthread might decrease how quickly the liver breaks down some medications. Taking goldthread along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking goldthread, talk to your healthcare provider if you are taking any medications that are changed by the liver.Some medications changed by the liver include cyclosporine (Neoral, Sandimmune), lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), and many others.

The information provided on this page is for reference purposes and is not meant to be used as a medical advice, diagnosis or treatment. Always consult with a medical professional. The content on this page has been provided with thanks by