Lorenzo's oil is a combination of two chemicals called erucic acid and oleic acid. People use Lorenzo's oil as a medicine.
Lorenzo's oil is used as a treatment for two related inherited conditions that affect the nervous system. These very rare conditions are called adrenoleukodystrophy (ALD), which occurs in children; and adrenomyeloneuropathy, which occurs in adults.
Lorenzo's oil is named after a child, Lorenzo Odone, who developed ALD. His parents discovered a mixture of fatty acids that seemed to slow progression of the disease. The mixture became known as “Lorenzo's oil.”
In the US, Lorenzo's oil is only available to patients participating in a clinical trial. For more information, contact the Kennedy Krieger Institute at 1-800-873-3377.
There is currently an effort to obtain Food and Drug Administration (FDA) approval of Lorenzo's oil as a prescription drug.
How it works
Adrenoleukodystrophy and adrenomyeloneuropathy are two rare genetic disorders that cause a large build-up of certain chemicals called very long-chain fatty acids. Lorenzo's oil might help prevent some of this build-up. The build-up of these fatty acids is thought to cause many serious problems throughout the brain and body.
Possibly EffectiveAdrenoleukodystrophy (ALD)
Lorenzo's oil might help prevent nervous system problems in children who have ALD, but haven't yet shown any symptoms. Lorenzo's oil probably does not help children who already have symptoms of ALD.
Lorenzo's oil seems to be safe when used under the care of health professionals. Side effects of Lorenzo's oil can include bruising and bleeding.
Pregnancy and breast-feeding: Not enough is known about the use of Lorenzo's oil duringpregnancyandbreast-feeding. Stay on the safe side and avoid use.Dosing considerations for Lorenzo's Oil.
Blood disorders that cause a decrease in blood platelets needed for clotting (thrombocytopenia) or a decrease in white cells needed to fight infections (neutropenia): Lorenzo's oil might make these conditions worse.
No information available.