Methylsulfonylmethane

18/Description

About

Methylsulfonylmethane (MSM) is a chemical found in green plants, animals, and humans. It can also be made in a laboratory. MSM has become popular because of the book The Miracle of MSM: The Natural Solution for Pain. But there is little published scientific research to support its use. Contrary to some literature that promotes MSM, there is no Recommended Dietary Allowance (RDA) for MSM or sulfur, which is in MSM. Sulfur deficiency has not been described in the medical literature.

People take MSM by mouth and apply it to the skin for chronic pain, osteoarthritis, joint inflammation, rheumatoid arthritis, osteoporosis, inflammation around the joints (bursitis), tendinitis, swelling around the tendons (tenosynovitis), musculoskeletal pain, muscle cramps, hardened skin condition called scleroderma, scar tissue, stretch marks, hair loss, wrinkles, protection against sun/wind burn, eye inflammation, oral hygiene, gum disease, wounds, cuts, and abrasions/accelerated wound healing.

People also take MSM by mouth for relief of allergies, chronic constipation, "sour stomach", ulcers, a bowel disease called diverticulosis, premenstrual syndrome (PMS), mood elevation, obesity, poor circulation, high blood pressure, and high cholesterol. It is also taken by mouth for type 2 diabetes, liver problems, Alzheimer's disease, to control snoring, lung disorders including emphysema and pneumonia, chronic fatigue syndrome, autoimmune disorders (systemic lupus erythematous), HIV infection and AIDS, and cancer (breast cancer and colon cancer).

MSM is also taken by mouth for eye inflammation, mucous membrane inflammation, temporomandibular joint (TMJ) problems, leg cramps, migraine, headaches, hangover, parasitic infections of the intestinal and urogenital tracts including Trichomonas vaginalis and Giardia, yeast infection, insect bites, radiation poisoning, and to boost the immune system.

How it works

MSM might supply sulfur to make other chemicals in the body.

Effectiveness

Possibly Effective
Muscle damage caused by exercise

Research shows that taking MSM daily beginning 10 days before a 14 km running exercise can help reduce muscle damage.

Hemorrhoids

Research shows that applying a specific gel containing MSM together with hyaluronic acid and tea tree oil (Proctoial, BSD Pharma, Italy) for 14 days can reduce pain, bleeding, and irritation in people with hemorrhoids.

Osteoarthritis

Research shows that taking MSM by mouth in two to three divided doses daily, either alone or together with glucosamine, can slightly reduce pain and swelling and improve function in people with osteoarthritis. But the improvements might not be clinically significant. Also, MSM might not improve stiffness or overall symptoms. Taking an MSM product (Lignisul, Laborest Italia S.p.A., Italy) together with boswellic acid (Triterpenol, Laborest Italia S.p.A., Italy) daily for 60 days might reduce the need for anti-inflammatory drugs but does not reduce pain. Also, early research suggests that taking a combination product containing MSM (AR7 Joint Complex, Robinson Pharma, Orange County, CA) by mouth for 12 weeks improves rating scores for joint pain and tenderness in people with osteoarthritis, but does not improve the appearance of joints.

Concerns

Possibly safe

MSM is POSSIBLY SAFE for most people when taken by mouth for up to 3 months or when applied to the skin in combination with other ingredients, such as silymarin or hyaluronic acid and tea tree oil, for up to 20 days. In some people, MSM might cause nausea, diarrhea, bloating, fatigue, headache, insomnia, itching, or worsening of allergy symptoms.

18/Warnings

Warnings

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking MSM if you arepregnantorbreast feeding. Stay on the safe side and avoid use.Dosing considerations for Methylsulfonylmethane.

Varicose veins and other circulatory problems (chronic venous insufficiency): Applying a lotion that contains MSM to the lower limbs can increase swelling and pain in people with varicose veins and other circulatory problems.

Interactions

No information available.

The information provided on this page is for reference purposes and is not meant to be used as a medical advice, diagnosis or treatment. Always consult with a medical professional.