Pancreatin is usually obtained from the pancreas of pigs or cows. The pancreas is an organ in animals and people that makes chemicals — amylase, lipase, and protease — that are needed for proper digestion. Pancreatin is used as medicine.
Pancreatin is used to treat digestion problems that result when the pancreas has been removed or is not working well. Cystic fibrosis or ongoing swelling (chronic pancreatitis) are two of the conditions that can cause the pancreas to function poorly.
Pancreatin is also used for intestinal gas (flatulence) or as a digestive aid.
How it works
Pancreatin contains amylase, lipase, and protease – chemicals that help to digest food. These chemicals are normally produced by the pancreas.
EffectiveInability to properly digest food (pancreatic insufficiency)
Taking pancreatin by mouth seems to improve the absorption of fat, protein, and energy in people with who are unable to digest food properly due to cystic fibrosis, pancreas removal, or an pancreas swelling (pancreatitis). Most studies have evaluated pancrelipase products, which contain more lipase enzyme than normal pancreatin. Lipase enzyme helps the body break down fat.
Pancreatin is LIKELY SAFE when taken by mouth by people with pancreas problems who cannot digest food properly. However, some pancreatin products contaminated by Salmonella bacteria have caused illness. Be sure to get pancreatin from a trusted source.Pancreatin can cause nausea, vomiting, diarrhea, mouth and skin irritation, and allergic reactions. High doses can cause problems such as high blood levels of a substance called uric acid, as well as colon damage.
Pregnancy and breast-feeding: There isn't enough information about the safety of using pancreatin duringpregnancyandbreast-feeding. It's best to avoid use unless you have been diagnosed with pancreas problems that make use of pancreatinessential.
ModerateAcarbose (Precose, Prandase)
Acarbose (Precose, Prandase) is used to help treat type 2 diabetes. Acarbose (Precose, Prandase) works by decreasing how quickly foods are broken down. Pancreatin seems to help the body break down some foods. By helping the body break down foods pancreatin might decrease the effectiveness of Acarbose (Precose, Prandase).