Sceletium is a plant from South Africa. It has a long history of use as a traditional medicine by tribes of South Africa. It has been used to enhance mood, cause relaxation, and euphoria. Traditionally, the roots and leaves were fermented and then chewed. It has also been used as snuff, smoked, or made into a tea or tincture.
How it works
Sceletium contains chemicals that are thought to work in the brain to cause sedation or sleepiness. However, there is very little reliable scientific information about how sceletium might work when taken by people.
Not ProvenAlcohol withdrawalAnxietyColicDecreasing appetiteDepressionPainRelaxationOther conditions
There is not enough information available to know if sceletium is safe.Some people who have used it report side effects including headaches, loss of appetite, and depression. There have also been reports of intoxication in people who use too much or who chew it shortly after fermentation.
Pregnancy and breast-feeding: Not enough is known about the safety of using sceletium duringpregnancyor whilebreast-feeding. Stay on the safe side and avoid using.Are there any interactions with medications?
ModerateSedative medications (CNS depressants)
Sceletium might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking sceletium along with sedative medications might cause too much sleepiness.Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.