Thiamine

Vitamins

18/Description

About

Thiamine is a vitamin, also called vitamin B1. Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and meat. It is often used in combination with other B vitamins, and found in many vitamin B complex products. Vitamin B complexes generally include vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin/niacinamide), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B12 (cyanocobalamin), and folic acid. However, some products do not contain all of these ingredients and some may include others, such as biotin, para-aminobenzoic acid (PABA), choline bitartrate, and inositol.

People take thiamine for conditions related to low levels of thiamine (thiamine deficiency syndromes), including beriberi and inflammation of the nerves (neuritis) associated with pellagra or pregnancy.

Thiamine is also used for digestive problems including poor appetite, ulcerative colitis, and ongoing diarrhea.

Thiamine is also used for AIDS and boosting the immune system, diabetic pain, heart disease, alcoholism, aging, a type of brain damage called cerebellar syndrome, canker sores, vision problems such as cataracts and glaucoma, and motion sickness. Other uses include preventing cervical cancer and progression of kidney disease in patients with type 2 diabetes.

Some people use thiamine for maintaining a positive mental attitude; enhancing learning abilities; increasing energy; fighting stress; and preventing memory loss, including Alzheimer's disease.

Healthcare providers give thiamine shots for a memory disorder called Wernicke's encephalopathy syndrome, other thiamine deficiency syndromes in critically ill people, alcohol withdrawal, and coma.

How it works

Thiamine is required by our bodies to properly use carbohydrates. It also helps maintain proper nerve function.

Effectiveness

Effective
Metabolic disorders

Taking thiamine by mouth helps correct certain inherited metabolic disorders, including Leigh's disease, maple syrup urine disease, and others.

Thiamine deficiency

Taking thiamine by mouth helps prevent and treat thiamine deficiency.

Brain disorder due to thiamine deficiency (Wernicke-Korsakoff syndrome)

Thiamine helps decrease the risk and symptoms of a specific brain disorder called Wernicke-Korsakoff syndrome (WKS). This brain disorder is related to low levels of thiamine. It is often seen in alcoholics. Giving thiamine shots seems to help decrease the risk of developing WKS and decrease symptoms of WKS during alcohol withdrawal.

Concerns

Likely safe

Thiamine is LIKELY SAFE when taken by mouth in appropriate amounts, although rare allergic reactions and skin irritation have occurred. It is also LIKELY SAFEwhen given appropriately intravenously (by IV) or as a shot into the muscle by a healthcare provider. Thiamine shots are an FDA-approved prescription product.Thiamine might not properly enter the body in some people who have liver problems, drink a lot of alcohol, or have other conditions.

18/Warnings

Warnings

Pregnancy and breast-feeding: Thiamine isLIKELY SAFEforpregnantorbreast-feeding women when taken in the recommended amount of 1.4 mg daily. Not enough is known about the safety of using larger amounts during pregnancy or breast-feeding.Dosing considerations for Thiamine.

Alcoholism and a liver disease called cirrhosis: Alcoholics and people with cirrhosis often have low levels of thiamine. Nerve pain in alcoholism can be worsened by thiamine deficiency. These people might require thiamine supplements.

Critical illness: People that are critically ill such as those that had surgery might have low levels of thiamine. These people might require thiamine supplements.

Hemodialysis: People undergoing hemodialysis treatments might have low levels of thiamine. They might require thiamine supplements.

Syndromes in which it is difficult for the body to absorb nutrients (malabsorption syndromes): People with malabsorption syndromes may have low levels of thiamine. The might require thiamine supplements.

Interactions

No information available.

The information provided on this page is for reference purposes and is not meant to be used as a medical advice, diagnosis or treatment. Always consult with a medical professional.